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The main consideration is blood pressure

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Zhang X, McAdam Marx C (2023) Short-term cost-effectiveness analysis of tirzepatide for the treatment of type 2 diabetes in the United States

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In a study of obese people with newly diagnosed type 2 diabetes, those taking Byetta lost nearly 13 pounds over a period of six months

In addition to its primary actions, secretin exerts effects on energy homeostasis, lipolysis in white adipose tissue (WAT), and thermogenesis in brown adipose tissue (BAT)