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doi:10.1186/s12958-018-0434-y

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A: Some people tolerate combinations, but irritation can increase

129131 The administration of pharmacological inhibitors targeting inflammasome components, such as NLRP3 or caspase-1 inhibitors, mitigates APAP-induced liver injury in preclinical models, highlighting the pivotal role of inflammasomes in modulating hepatic inflammation and damage

These improvements persisted for at least 2 weeks after treatment cessation, supporting a sustained symptomatic relief and skin barrier-restorative effects

10.1385/NMM:9:1:17 106 MausM.MarinP.IsralM.GlowinskiJ.PrmontJ