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Since cellular senescence is considered a natural defense mechanism against tumor development, and senescence inductions triggered by currently applied therapies can significantly impact their effectiveness, it is assumed that purposeful stimulation of senescence in cancer cells may be a promising direction in the development of anticancer therapy [8, 15, 55]

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acnes bacteria or regulate sebum production, which are key pathological factors in acne development

Month 1+: This is where the remodeling signals take full effect

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Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE