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[ 8 ] In humans, one study found that DSIP reduced circulating ACTH levels, while another found no effect on CRH-stimulated ACTH and cortisol secretion

The peptide contacting gut tissues directly may produce benefits regardless of systemic absorption levels

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Staining sections were examined and photographed with a digital camera (Olympus DP72) attached to a photomicroscope (Olympus BX51)

The key takeaway is that under normal usedrawing from an aluminum-covered vial into a transparent syringe and injecting within a minute or sothere is nothing to worry about