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By blocking NNMT, it increases intracellular NAD+ levels, which in turn activates sirtuins (like SIRT1), leading to improved metabolism and reduced fat storage

2.5 NeuronSchwann Cell Co-Culture Models Co-culture systems of neurons and Schwann cells have enabled us to generate myelin structures nearly equivalent to those in living bodies, thereby being recognized as useful tools to investigate neuron-Schwann cell interactions (Ogata et al., 2004)

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FCU (Figure 8) 15

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10.1007/s00125-017-4350-z 80