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Maple syrup urine disease Inborn errors of BCAA metabolism lead to thiamin-responsive branched-chain ketoaciduria, also known as maple syrup urine disease

An in vivo experimental study based on rat HH test model has reported that the aqueous extract of Ganoderma lucidum can improve neurotransmitter levels in HH animal models, prevent the surge of glucocorticoids and -synuclein, induce the upregulation of CREB/p-CREB/BDNF expression through ERK1/ERK2 to improve synaptic plasticity, and maintain redox homeostasis, to improve HH-related spatial memory deficits and neuronal damage (Sharma and Tulsawani, 2020)

J Allergy Clin Immunol (2002) 109(4):65868.10.1067/mai.2002.123302 14 ReberLLHernandezJDGalliSJ

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Figure 1 HCs were HIV, HCV, and HB seronegative, and mainly recruited pre-COVID-19 pandemic

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