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Bax protein is a proapoptotic member that acts by forming pores on the mitochondrial outer membrane, allowing cytochrome c to translocate into the cytoplasm, resulting in the loss of energy production and the activation of proteolytic cascade leading to apoptosis (Westphal et al., 2014)
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Troncoso R, Espinoza C, Snchez-Estrada A, Tiznado M, Garia HS (2005) Analysis of the isothiocyanates present in cabbage leaves extract and their potential application to control Alternaria rot in bell peppers
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Altered miRNA profiles have been reported in the cochlea following acoustic trauma, and in tinnitus models induced by other etiologies such as salicylate, suggesting that miRNA dysregulation may contribute to maladaptive responses to peripheral injury (Patel et al., 2013)