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doi: 10.1017/S0007114513001645

Interestingly, GLP-1 resistance during HFD feeding reduces enteric activation and NO production, which is due to changes in the gut microbiota (see the Gut microbiotabrain connection section) 72

Even if the underlying problem is treated appropriately and the digestive tract returns to normal, the vomiting, diarrhea, and weight loss may continuebut now because of the vitamin B12 deficiency, not the initial disease process

doi:10.1016/S0021-9258(18)57167-2

THC can influence metabolism and gastrointestinal function, and this could potentially affect the way GLP-1s are absorbed into the body, Snyder says

Patients with other pregnancies or medical or surgical complications were excluded from the study