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Fracture risk was lower in the GLP-1RA group when examining higher daily doses of the medications, when allowing follow-up to continue after medication change, and when examining hip fractures, specifically

GLP-1RAs, including semaglutide, liraglutide, and tirzepatide, are currently FDA approved for the treatment of obesity in patients with a body mass index (BMI) greater than or equal to 30 or a BMI greater than or equal to 27 in the setting of an obesity-related comorbidity, including asthma

Around 20% of daily water intake usually comes from food: so when GLP-1 medications suppress hunger and meal sizes shrink, overall fluid intake naturally declines

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists