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doi:10.1016/j.nbd.2024.106684 39

For patients with known liver disease or elevated baseline transaminases, obtaining liver function tests (LFTs) before initiating semaglutide provides a valuable reference point

4 Seven additional Phase 3 trials are evaluating retatrutide for obesity without osteoarthritis, type 2 diabetes, obstructive sleep apnea, chronic low back pain, liver disease, and cardiovascular outcomes

The full list of all the identified targets is available in Supplementary File 1

Most existed reports uncovered cAMP activity changes after residue substitutions and they were summarized in part 2

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