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reported that there were no apparent differences in serum acylcarnitine profiles among hypo-, hyper- and euthyroid states and inferred that the acylcarnitine profiles were relatively unremarkable in thyroid disease [25]

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Hazen demonstrated that elevated TMAO promotes platelet hyperreactivity and atherosclerosis, and multiple epidemiological studies have associated higher TMAO levels with adverse cardiovascular outcomes (Zhu et al., 2016

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