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Overdoses of vitamin B12 are rare since it has a low toxicity level as a water-soluble vitamin excreted through the urine

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doi: 10.1007/s11011-021-00791-8 14 BabinchakW

They should not be compared

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Surgery is generally reserved for cases with progressive neurological deficits, cauda equina syndrome (a surgical emergency), or persistent symptoms despite 6 to 12 months of conservative treatment