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Justice et al., 1 is prominently expressed in the forebrain including the isocortex throughout cortical layers II-VI, hippocampal formation at the CA1 level, basal ganglia within the globus pallidus and striatum, sensory systems and the amygdala (Justice et al., 1 was also detected in all segments of the mouse spinal cord throughout laminae II-V (Korosi et al., 2007)

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This fundamental mechanistic difference has implications for metabolic effects, hepatic fat handling, and potentially which patient populations benefit most

Comparison of intermittent fasting versus caloric restriction in obese subjects: A two year follow-up

Christophe Arbet-Engels, MD, Chief Medical Officer

That gap is not noise