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an unusual or allergic reaction to methylcobalamin, cobalt, other medicines, foods, dyes, or preservatives

Vitamin B12 is a water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function

They do not address underlying metabolic dysfunction and stop working when discontinued

Cool compresses applied for 15 to 30 minutes several times daily reduce inflammation and soothe itching without the drying or sensitization risks of topical products

Am J Pathol

For 2025, there are no major status changes where a substance changes from permitted to prohibited or vice versa, but the 2025 Prohibited List does include new examples of prohibited substances and a few clarifications