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PDI has two active sites, both of which are characterized by the presence of a CGHC motif, which either forms a disulphide for the enzyme to become active as an oxidase, or a dithiol for the enzyme to act as an isomerase

SAT1 was demonstrated to induce ferroptosis by elevating the expression of arachidonate 15-lipoxygenase (ALOX15)[42]

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Lycopene belongs to the class of carotenoids (plant pigments)

GBM constitutes the most malignant subtype of glioma and the most prevalent primary brain tumour in adults, accounting for 45.2% of cases [147]