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Studies have shown that thyroid autoimmunity is influenced by genetic variations in adhesion molecules (CD14, CD40), cytokines and their receptors, self-antigens, apoptosis-related gene products, and the promoter region of selenoprotein S (Klubo-Gwiezdzinska And Wartofsky 2022)

doi: 10.1016/j.ajog.2022.07.030 20 LockettJInderWJCliftonVL

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When blood sugar is extremely elevated, the kidneys reabsorb less glucose and consequently less water, which may cause severe (and potentially fatal) dehydration

Trace elements that have the potential to limit this efficiency include cobalt (converted to vitamin B12 in the lamb) and selenium

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