BCATs are the first enzymes in the BCAAs metabolic pathway, including BCAT c encoded by BCAT 1 gene, mainly expressed in the cytoplasm, and BCAT m encoded by BCAT 2 gene, which is expressed in the mitochondria
In developing regions like Nigeria, Kenya, and the Democratic Republic of Congo, the lack of adequate waste management infrastructure contributes to unchecked pharmaceutical discharge into water systems, leading to bioaccumulation and heightened AMR in aquatic biota [53]
It plays a central role in maintaining cellular redox balance, functioning in antioxidant defense, detoxification, and redox homeostasis (Lu, 2013
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Effect of Human Glutathione S-Transferase hGSTP1-1 Polymorphism on the Detoxification of Reactive Metabolites of Clozapine, Diclofenac and Acetaminophen. Toxicology Letters, vol
Annu Rev Plant Biol 50(1):4765