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For legitimate side-effect information, see our GLP-1 side effects guide

Data Availability Statement The data presented in this study are available on request from the corresponding author

Rare but Serious Risks: Serious adverse events are uncommon, but the class has a few important considerations: Pancreatitis: Post-marketing reports linked GLP-1 RAs to cases of acute pancreatitis

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Cyclic AMP-mediated pleiotropic effects of glucagon-like peptide-1 receptor activation

In fact AR231453, a selective GPR119 agonist, improves glucose tolerance and insulin sensitivity in both WT and Gpr119 cell / , suggesting how insulin release is independent from pancreatic GPR119 but depends on gut incretin release (330)