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Cohen J, Nassau DE, Patel P, Ramasamy R

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Moreover, the context-dependent nature of ferroptosiswhereby factors such as ROS levels, iron homeostasis, and the tumor microenvironment intricately modulate its dual rolehas yet to be fully elucidated

Application to A549 lung cancer cells incubated with CdCl and cisplatin for 24 and 48 h revealed significant glutathione depletion and multiple metabolic alterations, including elevated -glutamylcysteine levels