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doi: 10.1038/s41586-023-06265-4 42 YangWCCaoHLWangYZLiTTHuHYWanQet al

The prevalence of glaucoma is expected to rise to 111.8 million cases by 2040 [1]

The risk-benefit calculus for adding it to an existing longevity stack is favorable even without the preprint

It reduces post-injury fibrosis by modulating the expression of matrix metalloproteinases (MMPs), promotes the formation of new blood vessels, and stimulates muscle fiber regeneration

Larger subcutaneous injection volumes (above 0.5mL) can cause more local discomfort, swelling, and slower absorption

Some conditions that are especially benefited by increasing NAD+ levels are: See list of conditions benefitted by NAD+ Substance Abuse Depression Addiction Chronic Pain Sleep Disorders Brain Injury Autism Mitochondrial Disease Lyme Disease Chronic Fatigue Improving Physical Performance in Athletics Anxiety Neurodegeneration You will notice that many of the conditions mentioned involve suboptimal functioning of the brain and nervous system