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Improvements were also noted in steatosis scores, liver enzymes [60% reduction in alanine aminotransferase (ALT), 50% reduction in aspartate transaminase (AST) and 52% reduction in gamma-glutamyl transferase (GGT)], glycated hemoglobin A1c (HbA1c) (1.2% reduction), and body weight (12.3 kg reduction)

According to the Centers for Disease Control and Prevention (CDC), prolonged use of opioid-containing medications like Vicodin (hydrocodone/acetaminophen) and Percocet (oxycodone/acetaminophen) results in physical dependency, withdrawal symptoms, and substance use disorders

Metformin stabilizes blood sugar, which prevents the energy crashes that trigger hunger

& Gao, X.-M

Thats a huge jump from 30.4% in 1999