doi: 10.1016/j.canlet.2024.216911 116 ChenMZhangQZhengSGuoXCaoLRenYet al
Take those statistics with appropriate skepticism
Since GLP-1s slow digestion, toxins from contaminated food may linger longer and cause more severe symptoms
Grauer SM, Pulito VL, Navarra RL, Kelly MP, Kelley C, Graf R, et al
It has been proposed that hyperpigmentation in the epidermal basal layer as well as the presence of dermal melanophages may be due to faulty transfer of melanosomes from melanocytes to keratinocytes, resulting in a lack of melanosomes in keratinocytes in the upper epidermis and pigment incontinence in the dermis
The predicted interaction footprint extends further toward the intracellular region, yielding a broad contact network that plausibly stabilizes an activation-compatible receptor architecture from the extracellular face toward the cytoplasmic side (Figure 4)