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Glucagon receptor activation increases how much energy your body burns at rest

doi:10.1001/jama.2015.9676 Sorli C, Harashima SI, Tsoukas GM, Unger J, Karsbl JD, Hansen T, Bain SC

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Key variants in the GLP1R gene (rs6923761) and GIPR gene (rs1800437) influence receptor expression and signaling strength, partially determining whether you'll feel appetite suppression strongly by day two or more subtly by week two