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In diet-induced obese rats treated with SGLT2 inhibitors, lipolysis and circulating ketone body levels are increased [43, 44]
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Recently, several drugs have been designed on the basis of their ability to aggravate ER stress in cancer cells via the induction of oxidative stress
Mok TSK, Cortinovis DL, Majem M, Johnson ML, Mardjuadi FI, Zhao X, Siripurapu SV, Jiang Z, Wolf J
Additional mice (n = 3/group) were administered with MEDI4166 at 10 mg/kg or Ab#2.1_EX4 at 10 or 30 mg/kg to determine human Fc and GLP-1R active compound concentrations by taking blood samples at the following times post-dosing: 2 h, 4 h, 8 h, 1, 3, 7, 14 and 21 days