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That distinction matters, because it means the size of the resulting pulse still depends on where the endogenous somatostatin rhythm happens to be at the moment of stimulation a source of variability no reconstitution calculation can capture

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149 YabuuchiH.TamaiI.NezuJ.SakamotoK.OkuA.ShimaneM.et al (1999)

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A specialized transporter for the uptake of biotin and pantothenic acid was identified in cultured cells derived from the lining of the colon, suggesting that humans may be able to absorb pantothenic acid and biotin produced by intestinal bacteria (39)