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By combining MRS findings with clinical observations over time (regarding, for instance, treatment resistance and relapse/remission), the information becomes even more powerful in translation. In one current study, the team has used MRS to study functional deterioration in the brain after relapse of psychotic disorders
Paraffin sections were immunohistochemically stained using standard procedures
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics
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More relevant for targeting ECD was the study of bloodendothelium interactions, where HUVECs were divided into untreated (quiescent endothelium) and stimulated with phorbol-12-myristate-13-acetate (PMA) to mimic an inflammatory response before whole blood perfusion
The choroid epithelial interface of the BCB acts together with the BBB, maintaining neuron wellbeing (Johanson et al., 2011)
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