for developing a novel murine closed-skull traumatic brain injury (TBI) model and using it to demonstrate that the mouse skull, whether thinned or intact, is permeable to drugs, allowing "transcranial" drug delivery into the underlying cerebral cortex with consequent reduction in injury-related cell death when glutathione is delivered
Microneedling, also called Collagen Induction Therapy, is a minimally invasive technique
Coumarin , L-leucine , and 3-indolepropionic acid emerged as top-ranking features based on mean decrease in accuracy, indicating their relative importance as diet-responsive metabolites within this cohort
In certain cases, allergen identification can significantly improve treatment outcomes, guiding both avoidance strategies and therapeutic decisions (Table 1) [5]
Liu Y, Wang H, Liang Y, et al
Nat Rev Immunol 18:545558