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Lancet 1999;354:447-55

As CD breed dogs have proven a suitable animal model of naturally occurring IVD degeneration [9, 13], we advocate using this model to assess the (side) effects of novel regenerative treatments

The timing question that applies to GLP-1 medications broadly applies here as well, and the answer is largely personal preference

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Evidence suggests benefit but needs larger trials confirming

I see most people seeking these injections to address hyperpigmentation issues like dark spots, melasma, or uneven skin tone, citing rapid visible changes after multiple sessions