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An international study combining single-cell genomics, spatial transcriptomics and artificial intelligence has identified large-scale changes in three-dimensional genome organisation in Alzheimers-affected brain cells, establishing chromatin architecture as a previously overlooked component of the diseases molecular pathology and a potential framework for future therapeutic targeting

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A common pattern is thigh, abdomen, thigh, abdomen, rotating left and right within each region

Haemoglobin levels usually normalise within four to eight weeks

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