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In animal studies, it has been shown that prebiotics and synbiotics can y influence gene expression to modify -oxidation and lipogenesis, thus effecting liver fat infiltration, inflammation, and insulin resistance

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In addition, novel regulators such as RNA methylation enzymes (METTL3/14) that modulate GPX4 mRNA stability (176), or RhoA-mediated vascular remodeling that enhances iron leakage into subchondral bone (97), may offer new molecular targets

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Important Considerations Consult Your Provider: Always discuss dosage adjustments with your healthcare provider