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Analytical testing confirms greater than 99.8 % purity , assay content verified at 4.86 mg, molecular ion mass identified at 1815 Da and endotoxin levels measured at 0.009 EU/mg

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However, it is generally recommended to discard any reconstituted medication after 28 days to ensure potency and sterility

Critically, two of the efficacy studies were long-term investigations extending up to 24 weeks, providing meaningful data on sustained exposure safety

Tandon et al., 2022) the authors evaluated the quality of the clinical trial included in the qualitative synthesis, based on 5 items assessing the randomization process, blinding, and the dropout rate (i.e., the patients lost to follow-up)