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10.1038/s41568-022-00537-3 30 LimagneE.ThibaudinM.EuvrardR.BergerH.ChalonsP.VganF.et al (2017)

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Additionally, nanocurcumin reduced inflammation by decreasing the expressions of TNF-, IL-1, TLR4, NF-B p65, and high mobility group box 1 (HMGB1) (103)

Disruptions in iron metabolism lead to pathological conditions, with transferrin-Fe3+ complex formation occurring when transferrin binds external Fe3+ on the cell membrane, which is subsequently internalized by transferrin receptor 1 (24)

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