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We selected pAcF as the handles for constructing conjugates instead of other chemistry such as azide mediated click chemistry as the cyclopropane-tetrazine ligation employed in the pAcF system demonstrates superior bioorthogonality compared to azide-alkyne cycloadditions, effectively minimizing off-target reactions in complex cellular environments

This challenges the conventional treatment framework and demands a more sophisticated, tailored approach

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Alzoubi KH, Rababa'h AM, Owaisi A, Khabour OF (2017) L-carnitine prevents memory impairment induced by chronic REM-sleep deprivation

Prevention of Gastric Necrosis Produced by Alcohol, HCl, NaOH, Hypertonic NaCl, and thermal Injury