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Small molecules undergo hepatic metabolism before systemic exposure

These findings suggest the possibility of dissociation between DPP4 enzyme activity, the use of DPP4i and inflammatory markers in animals and humans

This is an educational research and dosing-context reference

The clinical trial most often cited is Leyden and colleagues' 2002 randomized 12-week trial of a GHK-Cu facial and eye cream in 71 women with photoaged skin [4]

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Shearer J, Shah S, MacInnis MJ, Shen-Tu G, Mu C