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Source: Brakedal et al., Cell Metabolism (2022)

Under UV exposure, ATRA reduces the expression of proteins like E3 ligase Hrd1, sustaining Nrf2 activity and contributing to photoprotection and repair mechanisms essential for melanocytes

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Some clinical trials have suggested that NAC supplementation may improve liver enzymes, insulin sensitivity, and markers of liver inflammation in patients with NAFLD, though the evidence base remains insufficient for clinical recommendations

Anthraquinone modifications can significantly upregulate the expression of glucose-regulated protein 78, activate transcription factor 4, and downregulate the expression of the essential ferroptosis protein GPX4