glp 1 side effects muscle pain Does GLP-1 Cause Cramps? Evidence and Management Muscle Loss with GLP-1 Medications:

10.1093/jn/114.10.1762 123

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This is possible, but given that innate inflammation in the form of microglial activation and macrophage infiltration is a universal response to most types of CNS injury (Rivest, 2009), we would argue that it remains equally plausible that in MS microglia/macrophages are instead reacting to some persistent underlying pathological process in an attempt to limit and repair the expanding white matter damage

Moreover, disease states appear to influence GLP-1R expression patterns