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PfGrx-dependent reduction kinetics for glutathionylated monothiol roGFP2 The glutaredoxin-dependent reduction of glutathionylated monothiol roGFP2 variants was analyzed in the presence and absence of GSH (Fig

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With iron-chelating properties and monoamine oxidase inhibitory activity, VK-28 derivatives (including M30, M32, and HLA20) target multiple neurodegenerative pathwaysthey suppress oxidative stress-related pathways (e.g., Keap1-Nrf2), modulate the AKT/mTOR pathway, and alleviate -syn aggregation (230)