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Both Genes were cloned via NcoI and NotI restriction sites into plasmid pETM20 and/or pETM11 (Dummler et al., 2005) yielding constructs pETM20- msadh or pETM11- msadh and pETM11- mdh

These GLP-1 receptors are located in regions that regulate appetite, reward, and mood

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Summary: A new study has unmasked the precise intracellular events triggered inside neurons by GLP-1 receptor agonists like semaglutide.The study utilizes real-time fluorescence imaging in mouse models to map how the drug alters cellular signaling to drive weight loss