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In the Phase II ZUPREME-1 trial, petrelintide monotherapy produced placebo-adjusted weight loss of up to 9% at 42 weeks, putting it closer to cagrilintide monotherapy from Novo Nordisk A/S (CSE:NOVO-B

These steps minimise copper coordination shifts and mechanical shear that drive aggregation, keeping the peptide in monomeric (single-molecule) form for optimal cellular uptake

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The largest population with a tendency toward low B12 is vegetarians and vegans