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The main contraindications for Lemon Bottle include pregnancy or breastfeeding, liver or kidney disease, autoimmune conditions, blood clotting disorders, active skin infections at the treatment site, allergy to bromelain (pineapple), lecithin, or riboflavin, diabetes, recent injectable treatments in the same area (past 4 weeks), and a history of keloid scarring

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For years, researchers avoided glucagon activation because glucagon raises blood sugar, which seemed counterproductive for a metabolic medication

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