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Although, the mucosal GSH levels achieved after NAC administration are still below control values, these findings suggest the existence of a critical threshold level of mucosal GSH that confers cytoprotection

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In some cases, dosing far exceeds anything studied in clinical trials

Moreover, the frequently-studied synthetic analogs of malarial hemozoin, such as -hematin, do not easily reveal hemozoin-related biological processes either

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They were also asked to make healthy diet and exercise choices for 3 months during the study