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Furthermore, all members of the SalB group displayed normal test results and no adverse responses, indicating a high level of safety (Liu et al., 2002)

The program is designed to meet regulatory requirements in specific states

The application process takes two to four weeks

Current safety data for 5-amino-1MQ appears favorable for short-term use (8-12 week cycles), with no significant toxicity observed in preclinical studies at therapeutic doses

It is worth noting that these investigators began VPA 48 h before infusion of epirubicin on each cycle to attempt to exploit synergism seen with this sequencing approach demonstrated in pre-clinical models (see below)