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They are often used when branded options are unavailable, not covered by insurance, or not a good fit for a patients needs

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Despite the better pathological complete response from oestrogen receptor negative tumours, surprisingly oestrogen receptor negative patients are known to have a worse overall survival, 12, 13 which was also observed in this cohort ( P =0.014) (Figure 4b)

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Study treatments were administered in the morning with approximately 200 mL of water and a standardized breakfast under direct supervision by the study personnel

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