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In contrast, we found that these metabolomic alterations led to a reduction in the plasma level of different metabolites including uridine, thymine, carnosine, theophylline, aspartate, taurine, serine, glutamate, tryptophan, arginine, and 53 other metabolites in the acute patients compared to HCs ( Supplementary Figures 6A, B )

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GLP-1 receptor agonists (GLP-1RAs) are designed to mimic the action of endogenous GLP-1 but have a longer duration of action, making them effective therapeutic agents for type 2 diabetes [40]