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Decreased appetite is technically a therapeutic effect, not a side effect, but it can feel distressing for patients who experience complete food aversion rather than gentle appetite reduction

doi: 10.1371/journal.pone.0089355 128 ZhouLXueXHouQ

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[DOI] [Google Scholar] 65.Bavaro S.L., De Angelis E., Barni S., Pilolli R., Mori F., Novembre E.M., Monaci L

Similar to folic acid deficiency, vitamin B 12 deficiency produces hyperhomocys-teinemia, which is an independent risk factor for atherosclerotic disease

102 , 915928, doi:10.1002/jps.23415 (2013)