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Research models evaluate these pathways by administering precise g doses of B12 and observing biochemical or physiological markers

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Duerr RH, Taylor KD, Brant SR et al (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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Given the heterogeneity of evidence across this field, greater interpretive weight was placed on human studies, well-characterized animal models, and recent high-quality reviews

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