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doi: 10.1097/md.0000000000016575, 66

D., Hashimoto, T., et al

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While some pathogens primarily use one mechanism to alter host physiology, others, including Salmonella and Escherichia coli, are capable of altering the cellular functions of the intestinal epithelium through multiple mechanisms [67]

Once you begin using a pen or vial, storage rules may shift depending on your specific formulation