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This remarkable selectivity stems from 5-amino-1MQs specific interaction with the nicotinamide-binding pocket of NNMT, rather than the SAM-binding site common to many methyltransferases

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Subsequent choices of interface parameters and functional module combinations are, in essence, concrete routes through which these overarching aims are pursued, and they form the basis for the design logic outlined in the following subsections [9, 31, 33, 37]

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The presence of Coliform could indicate the presence of other infection disease causing organisms