Cytochrome P450 (CYP) 3A4 primarily metabolizes phentermine but does not show extensive metabolism
Why Study Results Diverge Some studies have reported possible associations
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Mode of Action GLP-1 receptors are available in many part of the human body which allow the GLP-1 hormone to exert its functions and effects, reducing body weight, systolic blood pressure, HbA1c and lipid profile ( Figure 3 ) Figure 3: GLP-1 effect on different parts of the body
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In addition, they are being explored for their implications in reducing the risk of cardiovascular disease and cancer, and treating high blood pressure, kidney disease, autoimmune diseases and other conditions such as sleep apnea, fatty liver disease, Alzheimers disease, smoking cessation and substance use disorder