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In rodents, vagal stimulation increases corticotropin releasing hormone mRNA expression in the hypothalamus [11]

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What Your Doctor Should Know Before Prescribing Either Drug Any prescriber considering phentermine or tirzepatide should obtain a detailed cardiovascular history, recent blood pressure readings, and an EKG if the patient has hypertension, prior arrhythmia, or family history of sudden cardiac death

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Then, Parkin ubiquitinates outer mitochondrial membrane proteins to trigger selective autophagy [75, 82, 83]

This is an exciting example of how therapies developed for one disease may ultimately reshape the management of another